间充质干细胞来源外泌体在创面修复中的作用及其机制研究进展(6)
[17]Togliatto G，Dentelli P，Gili M，et al.Obesity reduces the pro-angiogenic potential of adipose tissue stem cell-derived extracellular vesicles (EVs) by impairing miR-126 content：impact on clinical applications[J].Int J Obes (Lond)，2016，40(1)：102-111.
[18]Kou X ，Xu X，Chen C，et al.The Fas/Fap-1/Cav-1 complex regulates IL-1RA secretion in mesenchymal stem cells to accelerate wound healing[J].Sci Transl Med，2018，10：432.
[19]Fang S，Xu C，Zhang Y，et al.Umbilical cord-derived mesenchymal stem cell-derived exosomal micrornas suppress myofibroblast differentiation by inhibiting the transforming growth factor-beta/smad2 pathway during wound healing[J].Stem Cells Transl Med，2016，5(10)：1425-1439.
, http://www.100md.com
[20]Hu L，Wang J，Zhou X，et al.Exosomes derived from human adipose mensenchymal stem cells accelerates cutaneous wound healing via optimizing the characteristics of fibroblasts[J].Sci Rep，2016，6：32993.
[21]Guo S，Dipietro LA.Factors affecting wound healing[J].J Dent Res，2010，89(3)：219-229.
[22]Wu P， Zhang B，Shi H，et al.MSC-exosome：a novel cell-free therapy for cutaneous regeneration[J].Cytotherapy，2018，20(3)：291-301.
, 百拇医药
[23]Singla DK.Stem cells and exosomes in cardiac repair[J].Curr Opin Pharmacol，2016，27：19-23.
[24]Than U，Guanzon D，Leavesley D，et al.Association of extracellular membrane vesicles with cutaneous wound healing[J].Int J Mol Sci，2017，18(5)：956.
[25]Wang X，Gu H，Qin D，et al.Exosomal miR-223 contributes to mesenchymal stem cell-elicited cardioprotection in polymicrobial sepsis[J].Sci Rep，2015，5(13721)：13721.
, http://www.100md.com
[26]Li X，Liu L，Yang J，et al.Exosome derived from human umbilical cord mesenchymal stem cell mediates mir-181c attenuating burn-induced excessive inflammation[J]. Bio Medicine，2016，8：72-82.
[27]Alexander M，Hu R，Runtsch M C，et al.Exosome-delivered microRNAs modulate the inflammatory response to endotoxin[J].Nat Commun，2015，6：7321.
[28]Singer AJ，Clark RA.Cutaneous wound healing[J].N Engl J Med，1999，341(10)：738-746.
, 百拇医药
[29]Shabbir A，Cox A，Rodriguez-Menocal L，et al.Mesenchymal stem cell exosomes induce proliferation and migration of normal and chronic wound fibroblasts，and enhance angiogenesis in vitro[J].Stem Cells Dev，2015，24(14)：1635-1647.
[30]Kim YJ，Yoo SM，Park H H，et al.Exosomes derived from human umbilical cord blood mesenchymal stem cells stimulates rejuvenation of human skin[J].Biochem Biophys Res Commun，2017，493(2)：1102-1108.
[31]Gospodarowicz D.Biological activities of fibroblast growth factors[J].Ann N Y Acad Sci，1991，638：1-8., http://www.100md.com(何强 张培华)
[18]Kou X ，Xu X，Chen C，et al.The Fas/Fap-1/Cav-1 complex regulates IL-1RA secretion in mesenchymal stem cells to accelerate wound healing[J].Sci Transl Med，2018，10：432.
[19]Fang S，Xu C，Zhang Y，et al.Umbilical cord-derived mesenchymal stem cell-derived exosomal micrornas suppress myofibroblast differentiation by inhibiting the transforming growth factor-beta/smad2 pathway during wound healing[J].Stem Cells Transl Med，2016，5(10)：1425-1439.
, http://www.100md.com
[20]Hu L，Wang J，Zhou X，et al.Exosomes derived from human adipose mensenchymal stem cells accelerates cutaneous wound healing via optimizing the characteristics of fibroblasts[J].Sci Rep，2016，6：32993.
[21]Guo S，Dipietro LA.Factors affecting wound healing[J].J Dent Res，2010，89(3)：219-229.
[22]Wu P， Zhang B，Shi H，et al.MSC-exosome：a novel cell-free therapy for cutaneous regeneration[J].Cytotherapy，2018，20(3)：291-301.
, 百拇医药
[23]Singla DK.Stem cells and exosomes in cardiac repair[J].Curr Opin Pharmacol，2016，27：19-23.
[24]Than U，Guanzon D，Leavesley D，et al.Association of extracellular membrane vesicles with cutaneous wound healing[J].Int J Mol Sci，2017，18(5)：956.
[25]Wang X，Gu H，Qin D，et al.Exosomal miR-223 contributes to mesenchymal stem cell-elicited cardioprotection in polymicrobial sepsis[J].Sci Rep，2015，5(13721)：13721.
, http://www.100md.com
[26]Li X，Liu L，Yang J，et al.Exosome derived from human umbilical cord mesenchymal stem cell mediates mir-181c attenuating burn-induced excessive inflammation[J]. Bio Medicine，2016，8：72-82.
[27]Alexander M，Hu R，Runtsch M C，et al.Exosome-delivered microRNAs modulate the inflammatory response to endotoxin[J].Nat Commun，2015，6：7321.
[28]Singer AJ，Clark RA.Cutaneous wound healing[J].N Engl J Med，1999，341(10)：738-746.
, 百拇医药
[29]Shabbir A，Cox A，Rodriguez-Menocal L，et al.Mesenchymal stem cell exosomes induce proliferation and migration of normal and chronic wound fibroblasts，and enhance angiogenesis in vitro[J].Stem Cells Dev，2015，24(14)：1635-1647.
[30]Kim YJ，Yoo SM，Park H H，et al.Exosomes derived from human umbilical cord blood mesenchymal stem cells stimulates rejuvenation of human skin[J].Biochem Biophys Res Commun，2017，493(2)：1102-1108.
[31]Gospodarowicz D.Biological activities of fibroblast growth factors[J].Ann N Y Acad Sci，1991，638：1-8., http://www.100md.com(何强 张培华)
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