腹腔镜手术治疗深部浸润型子宫内膜异位症的临床分析(1)
【摘要】 目的 研究分析腹腔镜手术治疗深部浸润型子宫内膜异位症的临床疗效及安全性。方法 84例深部浸润型子宫内膜异位症患者， 随机分为对照组及观察组， 各42例。对照组采用传统常规开腹手术方式治疗， 观察组应用腹腔镜手术进行治疗。比较两组患者的手术时间、术中出血量、视觉模拟评分法(VAS)评分、临床疗效以及并发症发生情况。结果 观察组手术时间短于对照组、术中出血量少于对照组、VAS评分低于对照组， 差异均具有统计学意义 (P<0.05)。观察组临床总有效率为90.48%， 明显高于对照组的66.67%， 差异具有统计学意义 (P<0.05)。观察组患者术后并发症发生率为23.81%， 明显低于对照组的45.24%， 差异具有统计学意义(P<0.05)。结论 胸腔镜手术治疗深部浸润型子宫内膜异位症具有手术时间短、创伤小、并发症少等优点， 更加安全、有效， 有利于患者的康复， 值得应用推广。
【关键词】 腹腔镜手术；深部浸润型子宫内膜异位症；临床疗效；安全性
DOI：10.14163/j.cnki.11-5547/r.2017.13.012
【Abstract】 Objective To study and analyze the clinical curative effect and safety of laparoscopic surgery in the treatment of deep infiltrating endometriosis. Methods A total of 84 deep infiltrating endometriosis patients were randomly divided into control group and observation group， with 42 cases in each group. The control group received traditional conventional laparotomy for treatment， and the observation group received laparoscopic surgery for treatment. Comparison were made on operation time， intraoperative bleeding volume， visual analogue scale (VAS) score， clinical curative effect and complications occurrence in two groups. Results The observation group had shorter operation time than the control group， less intraoperative bleeding volume than the control group， and lower VAS score than the control group. Their difference had statistical significance (P<0.05). The observation group had obviously higher total clinical effective rate as 90.48% than 66.67% in the control group， and the difference had statistical significance (P<0.05). The observation group had obviously lower incidence of postoperative complications as 23.81% than 45.24% in the control group， and the difference had statistical significance (P<0.05). Conclusion Laparoscopic surgery has advantages of short operation time， small invasion and less complications for the treatment of deep infiltrating endometriosis， and it is more safe， efficiency and beneficial to recovery of patients. So it is worthy of application and promotion.
【Key words】 Laparoscopic surgery； Deep infiltrating endometriosis； Clinical curative effect； Safety
子宮内膜异位症是临床中较为常见的一种妇科疾病， 主要指的是活性内膜细胞种植在患者子宫内膜以外的位置[1]。病灶组织浸润到腹膜以下的后盆腔内， 出现宫骶韧带缩短、变粗或结节， 子宫直肠陷凹变浅、消失， 阴道直肠隔结节等症状， 最终会导致反复性出血、疼痛以及不育[2]。传统的开腹外科手术虽然具有一定的疗效， 但是手术创伤大， 出血量多， 极易造成二次损伤。本研究就腹腔镜手术治疗深部浸润型子宫内膜异位症(deeply infiltrating endometriosis， DIE)的临床疗效及安全性进行统计分析， 报告如下。
1 资料与方法
1. 1 一般资料 随机抽选2015年7月～2016年7月在本院住院治疗的深部浸润型子宫内膜异位症患者84例， 以抽签的方式分为对照组及观察组， 各42例。对照组年龄21～55岁， 平均年龄(37.38±5.88)岁；观察组年龄22～57岁， 平均年龄(38.06±6.45)岁。两组患者一般资料比较， 差异无统计学意义(P>0.05)， 具有可比性。纳入标准：①月经规律；②手术执行前3个月未接受过相关激素类药物的治疗；③术前充分知情， 并且均签署了知情确认书；④整个治疗过程符合国际伦理委员会的相关要求。排除标准：①合并患有免疫性、内分泌、代谢性以及恶性肿瘤疾病；②伴有肝、肾以及凝血功能障碍性疾病；③严重的精神疾病以及认知功能障碍的患者；④治疗依从性低， 不愿意配合治疗的患者。, http://www.100md.com(王艳)
【关键词】 腹腔镜手术；深部浸润型子宫内膜异位症；临床疗效；安全性
DOI：10.14163/j.cnki.11-5547/r.2017.13.012
【Abstract】 Objective To study and analyze the clinical curative effect and safety of laparoscopic surgery in the treatment of deep infiltrating endometriosis. Methods A total of 84 deep infiltrating endometriosis patients were randomly divided into control group and observation group， with 42 cases in each group. The control group received traditional conventional laparotomy for treatment， and the observation group received laparoscopic surgery for treatment. Comparison were made on operation time， intraoperative bleeding volume， visual analogue scale (VAS) score， clinical curative effect and complications occurrence in two groups. Results The observation group had shorter operation time than the control group， less intraoperative bleeding volume than the control group， and lower VAS score than the control group. Their difference had statistical significance (P<0.05). The observation group had obviously higher total clinical effective rate as 90.48% than 66.67% in the control group， and the difference had statistical significance (P<0.05). The observation group had obviously lower incidence of postoperative complications as 23.81% than 45.24% in the control group， and the difference had statistical significance (P<0.05). Conclusion Laparoscopic surgery has advantages of short operation time， small invasion and less complications for the treatment of deep infiltrating endometriosis， and it is more safe， efficiency and beneficial to recovery of patients. So it is worthy of application and promotion.
【Key words】 Laparoscopic surgery； Deep infiltrating endometriosis； Clinical curative effect； Safety
子宮内膜异位症是临床中较为常见的一种妇科疾病， 主要指的是活性内膜细胞种植在患者子宫内膜以外的位置[1]。病灶组织浸润到腹膜以下的后盆腔内， 出现宫骶韧带缩短、变粗或结节， 子宫直肠陷凹变浅、消失， 阴道直肠隔结节等症状， 最终会导致反复性出血、疼痛以及不育[2]。传统的开腹外科手术虽然具有一定的疗效， 但是手术创伤大， 出血量多， 极易造成二次损伤。本研究就腹腔镜手术治疗深部浸润型子宫内膜异位症(deeply infiltrating endometriosis， DIE)的临床疗效及安全性进行统计分析， 报告如下。
1 资料与方法
1. 1 一般资料 随机抽选2015年7月～2016年7月在本院住院治疗的深部浸润型子宫内膜异位症患者84例， 以抽签的方式分为对照组及观察组， 各42例。对照组年龄21～55岁， 平均年龄(37.38±5.88)岁；观察组年龄22～57岁， 平均年龄(38.06±6.45)岁。两组患者一般资料比较， 差异无统计学意义(P>0.05)， 具有可比性。纳入标准：①月经规律；②手术执行前3个月未接受过相关激素类药物的治疗；③术前充分知情， 并且均签署了知情确认书；④整个治疗过程符合国际伦理委员会的相关要求。排除标准：①合并患有免疫性、内分泌、代谢性以及恶性肿瘤疾病；②伴有肝、肾以及凝血功能障碍性疾病；③严重的精神疾病以及认知功能障碍的患者；④治疗依从性低， 不愿意配合治疗的患者。, http://www.100md.com(王艳)